Flavor release from spray-dried amorphous matrix: Effect of lactose content and water plasticization
نویسندگان
چکیده
منابع مشابه
Determination of Amorphous Content of Spray Dried Lactose by Solution
In the injection moulding process the manufactured plastic components may carry asignificant amount of charge which has undesirable consequences in some applications e.g.in dry powder inhalers (DPI's). In high resistivity polymers, the charge may lie in the bulk ofthe material which prevents typical neutralizing procedures such as use of ionizers. Insteadof neutralizing the ...
متن کاملRelease characteristics of flavor from spray-dried powder in boiling water and during rice cooking.
The release characteristics of flavor in boiling water and the flavor retention in the rice after cooking were investigated by using spray dried powder in encapsulated in or emulsified with d-limonene or ethyl n-hexanoate in cyclodextrin and maltodextrin, or in gum arabic and maltodextrin. The behavior of flavor release into the boiling water was well simulated by Avrami's equation. The retenti...
متن کاملSpray-Dried Lactose
pray-dried (SD) lactose was introduced to the pharmaceutical market in the 1960s as an excipient that enables direct compression of formulations in a simple manufacturing process (1). To this day, lactose remains one of the most popular excipients for active pharmaceutical ingredients (APIs) whose dose makes them suitable for direct compression. Several manufacturers make and sell SD lactose, a...
متن کاملStabilization of the Amorphous Structure of Spray-Dried Drug Nanoparticles.
The bioavailability of hydrophobic drugs strongly increases if they are formulated as amorphous materials because the solubility of the amorphous phase is much higher than that of the crystal. Moreover, the stability of these particles against crystallization during storage increases with decreasing particle size. Hence, it is advantageous to formulate poorly water soluble drugs as amorphous na...
متن کاملTemperature-induced crystallization and compactibility of spray dried composite particles composed of amorphous lactose and various types of water-soluble polymer.
The purpose of this study was to investigate the temperature-induced crystallization and the compactibility of the composite particles containing amorphous lactose and various types of polymers. The composite particles were prepared by spray-drying an aqueous solution of lactose and various types of gel forming water-soluble polymers at various formulating ratios. The stabilizing effect of hydr...
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ژورنال
عنوان ژورنال: Food Research International
سال: 2016
ISSN: 0963-9969
DOI: 10.1016/j.foodres.2016.06.003